polynucleotides
Manchester

Polynucleotides in Manchester

Book from 19+ сlinics near you
SEPTRE CLINICALS
star
5.0
(1 Review)
£££
Verified Partner
Verified Partner
M20 6UR, 115A Lapwing Lane, ManchesterM20 6UR, 115A Lapwing Lane, Manchester
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I had Botox done at Septer Clinical back in May and I’m really happy with the results — it still looks great months later! I was quite nervous beforehand as I’m scared of needles, but the practitioner was incredibly patient, gentle, and reassuring throughout the whole process. The results look natural and gave me a real confidence boost. I’d definitely recommend Septer Clinical to anyone considering aesthetic treatments.

I had Botox done at Septer Clinical back in May and I’m really happy with the results — it still looks great months later! I was quite nervous beforehand as I’m scared of needles, but the practitioner was incredibly patient, gentle, and reassuring throughout the whole process. The results look natural and gave me a real confidence boost. I’d definitely recommend Septer Clinical to anyone considering aesthetic treatments.

VB Health
star
5.0
(113 reviews)
£££
OL4 4TZ, Jackson Street, Springhead, ManchesterOL4 4TZ, Jackson Street, Springhead, Manchester
Get directionsGet directions to VB Health
✨ Just had the most amazing experience at VB Health with Vicki for my polynucleotide treatment. From start to finish, I felt so well looked after — the whole team made sure I was comfortable, informed, and cared for every step of the way. The treatment itself was carried out perfectly with excellent before and aftercare. I’m so pleased with the results already! Highly recommend! 💖🙌 #VBHealth #PolynucleotideTreatment #SkinConfidence

✨ Just had the most amazing experience at VB Health with Vicki for my polynucleotide treatment. From start to finish, I felt so well looked after — the whole team made sure I was comfortable, informed, and cared for every step of the way. The treatment itself was carried out perfectly with excellent before and aftercare. I’m so pleased with the results already! Highly recommend! 💖🙌 #VBHealth #PolynucleotideTreatment #SkinConfidence

The Aesthetics Doctors MCR
star
5.0
(38 reviews)
£££
M3 3BN, 64 Bridge Street, ManchesterM3 3BN, 64 Bridge Street, Manchester
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I have been to visit the Aesthetic Doctors a couple of times now and I could not recommend enough. Their knowledge, professionalism, and attention to detail are truly invaluable. They take the time to listen, explain everything thoroughly, and ensure you’re confident with every decision. The results have always exceeded my expectations, and I really appreciate how natural and refreshed I look afterwards.

I have been to visit the Aesthetic Doctors a couple of times now and I could not recommend enough. Their knowledge, professionalism, and attention to detail are truly invaluable. They take the time to listen, explain everything thoroughly, and ensure you’re confident with every decision. The results have always exceeded my expectations, and I really appreciate how natural and refreshed I look afterwards.

Derma Transform Aesthetics - Dr Kemi
star
5.0
(31 reviews)
£££
M21 8AG, 559 Barlow Moor Road, ManchesterM21 8AG, 559 Barlow Moor Road, Manchester
Get directionsGet directions to Derma Transform Aesthetics - Dr Kemi
Had a wonderful experience with Farzana. She makes you feel comfortable and explains everything she is doing very clearly. Clean and professional clinic and will definitely be back.

Had a wonderful experience with Farzana. She makes you feel comfortable and explains everything she is doing very clearly. Clean and professional clinic and will definitely be back.

Dr Naz Clinics - Manchester
star
5.0
(28 reviews)
£££
M4 1ET, 3 Kelvin Street, ManchesterM4 1ET, 3 Kelvin Street, Manchester
Get directionsGet directions to Dr Naz Clinics - Manchester
I had an amazing experience with Dr. Naz. She’s incredibly knowledgeable and takes the time to explain everything clearly. She truly listens to your concerns and tailors a treatment plan just for you. I’ve never felt so confident in a skincare professional before. I’m so grateful for her expertise and would highly recommend her to anyone

I had an amazing experience with Dr. Naz. She’s incredibly knowledgeable and takes the time to explain everything clearly. She truly listens to your concerns and tailors a treatment plan just for you. I’ve never felt so confident in a skincare professional before. I’m so grateful for her expertise and would highly recommend her to anyone

skiin
star
5.0
(25 reviews)
£££
M1 1FL, 75 Lever Street, ManchesterM1 1FL, 75 Lever Street, Manchester
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Thoroughly enjoyed my experience at Skiin. Dr Tina really understood the assignment! Pre wedding skin glow up was exactly what I got and she is so good at recommending products for my changing skin needs! Highly recommend!

Thoroughly enjoyed my experience at Skiin. Dr Tina really understood the assignment! Pre wedding skin glow up was exactly what I got and she is so good at recommending products for my changing skin needs! Highly recommend!

Didsbury Medical Clinic
star
5.0
(19 reviews)
£££
M20 2YY, Wilmslow Road, ManchesterM20 2YY, Wilmslow Road, Manchester
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Excellent experience with Dr Fida, he is extremely knowledgable and passionate about what he does. I was put at ease instantly. Really happy with my treatment

Excellent experience with Dr Fida, he is extremely knowledgable and passionate about what he does. I was put at ease instantly. Really happy with my treatment

CLNiK94 - Medical Aesthetics & Skincare Solutions
star
5.0
(17 reviews)
£££
M3 3BN, 64 Bridge Street, ManchesterM3 3BN, 64 Bridge Street, Manchester
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Had a consultation for both Botox and skin boosters with Dr Cal, was really impressed with the service. Ended up going with polynucleotides and already loving the results. Would highly recommend Dr Cal to anyone in Manchester!

Had a consultation for both Botox and skin boosters with Dr Cal, was really impressed with the service. Ended up going with polynucleotides and already loving the results. Would highly recommend Dr Cal to anyone in Manchester!

Image placeholder
star
5.0
(17 reviews)
£££
M3 3BN, 64 Bridge Street, ManchesterM3 3BN, 64 Bridge Street, Manchester
Get directionsGet directions to TWEAKS
I've been having treatments with Nill for a while now and I cannot reccomend her enough. It is clear to see Nill's medical training in her thorough approach to consultation, discussion of risks and expectations of results. Nill always works with me to make sure I'm happy with the overall result. Added to this Nill is such a lovely, kind person who will instantly put you at ease. I wouldn't trust anyone else with my face now!

I've been having treatments with Nill for a while now and I cannot reccomend her enough. It is clear to see Nill's medical training in her thorough approach to consultation, discussion of risks and expectations of results. Nill always works with me to make sure I'm happy with the overall result. Added to this Nill is such a lovely, kind person who will instantly put you at ease. I wouldn't trust anyone else with my face now!

Manchester Aesthetics Clinic
M40 0HW, 453 Lightbowne Road, ManchesterM40 0HW, 453 Lightbowne Road, Manchester
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I had laser hair removal sessions with Sam and Julie. The girls are so friendly and lovely. I felt very comfortable throughout the treatments and the laser is literally pain free. The clinic is very inviting, clean and welcoming. I really enjoyed my experience here and look forward to future treatments. Thank you , from Shazia x

I had laser hair removal sessions with Sam and Julie. The girls are so friendly and lovely. I felt very comfortable throughout the treatments and the laser is literally pain free. The clinic is very inviting, clean and welcoming. I really enjoyed my experience here and look forward to future treatments. Thank you , from Shazia x

Lumiere Clinic Manchester
star
4.9
(164 reviews)
£££
M15 4QN, 38 City Road East, ManchesterM15 4QN, 38 City Road East, Manchester
Get directionsGet directions to Lumiere Clinic Manchester
Had an excellent experience having Dermal fillers from Dr Nicole Chiang. She is highly skilled with injectables, explained my treatment in detail, very pleased with my natural results. I will be booking future appointments at Lumiere Clinic.

Had an excellent experience having Dermal fillers from Dr Nicole Chiang. She is highly skilled with injectables, explained my treatment in detail, very pleased with my natural results. I will be booking future appointments at Lumiere Clinic.

Dermaskin Clinic
star
4.9
(117 reviews)
£££
M3 3EJ, 66 Quay Street, ManchesterM3 3EJ, 66 Quay Street, Manchester
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Dr Vik is highly knowledgable and skilled, lovely Botox results. Will be visiting for further work next month. Lovely guy and the receptionist is so lovely and helpful too A* Service

Dr Vik is highly knowledgable and skilled, lovely Botox results. Will be visiting for further work next month. Lovely guy and the receptionist is so lovely and helpful too A* Service

Skin HD
star
4.9
(99 reviews)
£££
M21 0RQ, 2 Railway Terrace, ManchesterM21 0RQ, 2 Railway Terrace, Manchester
Get directionsGet directions to Skin HD
I chose to use Skin HD based on the amazing reviews and so glad I did. I had a consultation with Helena about my aging. After a horrible injury and subsequent surgeries I’ve aged so much in a few years. I explained that at my age I expect some lines but mainly just wanted to look less knackered!

She recommended polyneuliotides as a course of 3 with results showing mostly after the 3rs threatment.

After one treatment I can see results and when I went back today for my second Helena’s reaction was great! She could see the difference straight away. She’s so lovely and even though the injections hurt a lot we have some lovely chats during it.

Highly recommend this place. And shout out to Yasmin on reception she’s so lovely too!

I chose to use Skin HD based on the amazing reviews and so glad I did. I had a consultation with Helena about my aging. After a horrible injury and subsequent surgeries I’ve aged so much in a few years. I explained that at my age I expect some lines but mainly just wanted to look less knackered! She recommended polyneuliotides as a course of 3 with results showing mostly after the 3rs threatment. After one treatment I can see results and when I went back today for my second Helena’s reaction was great! She could see the difference straight away. She’s so lovely and even though the injections hurt a lot we have some lovely chats during it. Highly recommend this place. And shout out to Yasmin on reception she’s so lovely too!

CLNQ Manchester
star
4.9
(51 reviews)
£££
M15 4YB, 11 Owen Street, ManchesterM15 4YB, 11 Owen Street, Manchester
Get directionsGet directions to CLNQ Manchester
I can not fault CLNQ or Dr Nassab for their amazing work. I felt so looked after from the get go.

Whenever I had a question or concern before, during or after surgery, there was always someone to help so thank you to Helena for always being outstanding, you are a credit to the team!

The team at Wilmslow Private Hospital are all so so talented. I felt like I was in safe hands throughout the whole surgery experience. The service truly is next to none.

If you're debating surgery, Dr Nassab and his team are the ones for you!

Thank you again to everyone involved.

You are remarkable!

I can not fault CLNQ or Dr Nassab for their amazing work. I felt so looked after from the get go. Whenever I had a question or concern before, during or after surgery, there was always someone to help so thank you to Helena for always being outstanding, you are a credit to the team! The team at Wilmslow Private Hospital are all so so talented. I felt like I was in safe hands throughout the whole surgery experience. The service truly is next to none. If you're debating surgery, Dr Nassab and his team are the ones for you! Thank you again to everyone involved. You are remarkable!

The Academy Clinic Manchester (Formerly SkinViva Clinic)
star
4.8
(238 reviews)
£££
M3 3HN, 19B Quay Street, ManchesterM3 3HN, 19B Quay Street, Manchester
Get directionsGet directions to The Academy Clinic Manchester (Formerly SkinViva Clinic)
Thank you girls for amaizing,friendly attitude.
Service was super profesional and I am very happy to meet you all.
The resuls already is amaizing.
I did botox and cheek filter.
Looks perfect 👌👌👌👌

Thank you girls for amaizing,friendly attitude. Service was super profesional and I am very happy to meet you all. The resuls already is amaizing. I did botox and cheek filter. Looks perfect 👌👌👌👌

Skin Doctor Manchester
star
4.8
(151 reviews)
£££
M20 2WR, 40 Lapwing Lane, ManchesterM20 2WR, 40 Lapwing Lane, Manchester
Get directionsGet directions to Skin Doctor Manchester
Amir and his team are fantastic. I’ve been going to Amir since the clinic opened and he always creates the most immaculate results - I won’t go anywhere else :)

Amir and his team are fantastic. I’ve been going to Amir since the clinic opened and he always creates the most immaculate results - I won’t go anywhere else :)

Dr Nicole Dermatology
star
4.8
(123 reviews)
£££
M15 4QN, 40 City Road East, ManchesterM15 4QN, 40 City Road East, Manchester
Get directionsGet directions to Dr Nicole Dermatology
Dr Nicole is fantastic! She is incredibly talented. I don’t worry about a thing and let her work her magic. I’m always amazed with the results! I’ve been seeing Dr Nicole for a while and I cannot recommend her highly enough! Thank you Dr Nicole.

Dr Nicole is fantastic! She is incredibly talented. I don’t worry about a thing and let her work her magic. I’m always amazed with the results! I’ve been seeing Dr Nicole for a while and I cannot recommend her highly enough! Thank you Dr Nicole.

Dr Anatalia Aesthetics
star
4.7
(123 reviews)
£££
M21 8HA, 264 Barlow Moor Road, ManchesterM21 8HA, 264 Barlow Moor Road, Manchester
Get directionsGet directions to Dr Anatalia Aesthetics
Dr Kasim and Katy were amazing with my son today. He needed 2 teeth out in preparation for braces and was quite anxious. They were very professional and kind, always checking that he was ok during the procedure and explaining everything in great detail. Thank you

Dr Kasim and Katy were amazing with my son today. He needed 2 teeth out in preparation for braces and was quite anxious. They were very professional and kind, always checking that he was ok during the procedure and explaining everything in great detail. Thank you

The Medika Clinic
star
4.6
(75 reviews)
£££
M3 3AT, 3 Hardman St, ManchesterM3 3AT, 3 Hardman St, Manchester
Get directionsGet directions to The Medika Clinic
The service in Medika is consistently excellent! After my first microneedling session with Rocio, I’m noticing a significant improvement in my skin - it looks more rejuvenated and refreshed. Looking forward to future sessions!

The service in Medika is consistently excellent! After my first microneedling session with Rocio, I’m noticing a significant improvement in my skin - it looks more rejuvenated and refreshed. Looking forward to future sessions!

New to Polynucleotides?

New to Polynucleotides?

Learn what this treatment is and how it works.

Learn more

reviews

Aisha Abdulkarim-0-starAisha Abdulkarim-1-starAisha Abdulkarim-2-starAisha Abdulkarim-3-starAisha Abdulkarim-4-star

✨ Just had the most amazing experience at VB Health with Vicki for my polynucleotide treatment. From start to finish, I felt so well looked after — the whole team made sure I was comfortable, informed, and cared for every step of the way. The treatment itself was carried out perfectly with excellent before and aftercare. I’m so pleased with the results already! Highly recommend! 💖🙌 #VBHealth #PolynucleotideTreatment #SkinConfidence

Aisha Abdulkarim

Aisha Abdulkarim

June 19
S B-0-starS B-1-starS B-2-starS B-3-starS B-4-star

I had such a wonderful experience at Dr Yusra Clinic in Manchester. From the moment I arrived, the team made me feel welcomed, informed, and completely at ease. I’ve had skin boosters and polynucleotides done here and couldn’t be happier with the results. The entire process was clearly explained to me beforehand, which really helped calm any nerves I had. I had the pleasure of meeting Dr Yusra hersel, she was incredibly warm, knowledgeable, and reassuring. Her expertise is immediately clear, and you can tell she genuinely cares about achieving the best, most natural results for each client. I also saw Jenna twice, and she was just as amazing, professional, kind, and attentive. She took the time to talk me through everything and answered all my questions with patience and care. Thanks to her skill and gentle approach, I experienced minimal to no bruising, which I was really impressed by. Overall, the clinic is immaculate, beautifully designed, and run by people who truly know what they’re doing. I would 100% recommend Dr Yusra Clinic to anyone considering skin treatments, you’ll be in safe, skilled hands.

S B

S B

June 11
Bew P-0-starBew P-1-starBew P-2-starBew P-3-starBew P-4-star

Had a consultation for both Botox and skin boosters with Dr Cal, was really impressed with the service. Ended up going with polynucleotides and already loving the results. Would highly recommend Dr Cal to anyone in Manchester!

Bew P

Bew P

July 3
Jo Evans-stolt-0-starJo Evans-stolt-1-starJo Evans-stolt-2-starJo Evans-stolt-3-starJo Evans-stolt-4-star

I chose to use Skin HD based on the amazing reviews and so glad I did. I had a consultation with Helena about my aging. After a horrible injury and subsequent surgeries I’ve aged so much in a few years. I explained that at my age I expect some lines but mainly just wanted to look less knackered! She recommended polyneuliotides as a course of 3 with results showing mostly after the 3rs threatment. After one treatment I can see results and when I went back today for my second Helena’s reaction was great! She could see the difference straight away. She’s so lovely and even though the injections hurt a lot we have some lovely chats during it. Highly recommend this place. And shout out to Yasmin on reception she’s so lovely too!

Jo Evans-stolt

Jo Evans-stolt

April 25
About Polynucleotides

About Polynucleotides

If you're looking for Polynucleotides in Manchester, MARBL makes it easy to compare medical-led clinics in one place. You can compare 19+ clinics for Polynucleotides in Manchester side by side. Prices typically range from around £100 to £700, depending on the clinic, treatment area and number of sessions. All clinics on MARBL are medical-led and carefully vetted – we list only around 10% of clinics in the UK that meet our safety and quality standards. Browse verified reviews and book your appointment online in just a few clicks.

Polynucleotides uses DNA-derived molecules to promote cellular repair, enhance hydration, and stimulate natural skin regeneration. This cutting-edge treatment activates natural healing processes at a cellular level to address aging, damage, and overall skin quality. The bio-regenerative therapy offers both immediate and progressive benefits through enhanced tissue repair and regeneration.

On MARBL, every clinic offering polynucleotides is vetted for treatment expertise, comprehensive safety protocols, and quality care standards. Treatments are performed by trained specialists with expertise in advanced aesthetic procedures. Each clinic listing includes transparent pricing, detailed procedure information, and guidance on achieving optimal results through professional care.

Polynucleotide sessions typically take 30-45 minutes per treatment, with initial improvements visible within 2-3 weeks and significant tissue regeneration apparent after completing 3-4 session series. You can compare certified specialists near you, check real-time availability, view verified reviews, and book polynucleotides sessions directly through MARBL — achieving your aesthetic goals has never been more convenient.

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Explore the best clinics for Polynucleotides near you – start by picking your city

FAQs

Polynucleotides are injectable treatments made from purified chains of DNA molecules, typically derived from salmon or trout sperm. These biostimulators work at a cellular level to promote skin regeneration, repair and rejuvenation. When injected into the skin, polynucleotides help to stimulate fibroblast activity, which in turn boosts the production of collagen and elastin, improves hydration and supports natural healing processes. The treatment is designed to improve overall skin quality, texture and tone rather than add volume or change facial structure. Polynucleotides are particularly popular for addressing concerns like crepey skin, fine lines, dullness, under-eye hollows, acne scarring and general signs of ageing.

In Manchester, clinics set different fees so prices for Polynucleotides can vary. In Manchester, the price of Polynucleotides typically ranges from around £280 to £800. Prices depend on the exact product used, whether you need a single session or a course, the practitioner’s experience and the treatment area and goals. Search for the price of Polynucleotides in Manchester to compare clinics and understand how much Polynucleotides costs locally. You can find the exact, up-to-date price for this treatment in the catalogue

A polynucleotide treatment involves a series of small injections delivered into the skin using a fine needle or cannula. During your appointment, the practitioner will cleanse the treatment area and may apply numbing cream for comfort. The polynucleotide solution is then injected at multiple points across the target area, such as the face, under-eyes, neck or hands. You may experience mild stinging or pressure during the procedure, and some small bumps or redness immediately afterwards, which typically settle within a few hours to a day. The treatment works gradually by stimulating your skin's natural regeneration processes rather than providing instant volume, so results develop over several weeks as collagen production increases and skin quality improves. Most practitioners recommend a course of treatments spaced a few weeks apart for optimal results.

Polynucleotides have shown promising results in clinical studies and real-world use, particularly for improving skin quality, hydration, elasticity and texture. They work by stimulating the body's natural repair mechanisms rather than simply filling or plumping the skin, which means results tend to look natural and develop gradually. Many people report improvements in skin tone, reduced appearance of fine lines, better hydration and a more refreshed overall appearance. However, effectiveness varies depending on individual factors such as age, skin condition, lifestyle and the severity of concerns being treated. Polynucleotides work best for people looking to improve skin quality and slow down visible signs of ageing, but they are not suitable for dramatic lifting, significant volume loss or deep wrinkles, where other treatments may be more appropriate. A consultation with an experienced practitioner can help determine if polynucleotides are right for your specific concerns.

Polynucleotides work gradually, as they stimulate your skin's natural regeneration processes rather than providing immediate visible changes. Most people begin to notice subtle improvements in skin hydration, texture and radiance within 2 to 4 weeks after their first treatment. More significant results, such as improved elasticity, reduced fine lines and overall skin quality, typically become apparent after completing a full course of treatments, usually over 6 to 8 weeks. The timeline can vary depending on your age, skin condition, the area being treated and how your body responds to the treatment. Because results develop progressively, patience is important, and it can take up to 3 months to see the full benefits. Your practitioner will be able to give you a more personalised timeline based on your individual treatment plan.

The results from polynucleotide treatments typically last between 6 to 12 months, though this varies from person to person. Because polynucleotides work by stimulating your body's natural collagen and elastin production rather than simply adding temporary volume, the improvements can have a longer-lasting effect compared to some other treatments. Factors that influence how long results last include your age, skin quality, lifestyle, sun exposure, skincare routine and whether you have maintenance treatments. Most practitioners recommend an initial course of 2 to 3 sessions spaced a few weeks apart, followed by maintenance treatments once or twice a year to sustain the improvements. The regenerative effects can continue to develop even after the treatment course is complete, as your skin's natural repair processes remain active.

Polynucleotides are generally considered safe when administered by a qualified and experienced practitioner in a clinical setting. The treatment has been used in aesthetic medicine for several years and has a good safety profile. Because polynucleotides are biocompatible and similar to naturally occurring molecules in the human body, the risk of allergic reactions is low. However, as with any injectable treatment, there are potential side effects such as temporary redness, swelling, bruising, tenderness or small bumps at injection sites, which typically resolve within a few days. Rare complications can include infection, prolonged swelling or uneven results. It is essential to choose a reputable, trained practitioner who follows proper hygiene and injection techniques. Always disclose your full medical history, any allergies, medications or existing health conditions during your consultation to ensure the treatment is appropriate for you.

Before polynucleotide treatment, people often have concerns such as dull or tired-looking skin, fine lines, crepey texture, loss of elasticity, uneven skin tone, under-eye hollows or early signs of ageing. After completing a course of polynucleotide treatments, the skin typically appears more hydrated, smoother, firmer and more radiant, with a noticeable improvement in overall skin quality and texture. Fine lines may appear softer, and the skin often has a healthier, more youthful glow. Because polynucleotides work gradually by stimulating natural regeneration, the changes tend to look subtle and natural rather than dramatically altered. Results continue to develop over several weeks and months as collagen production increases. The extent of improvement varies based on individual factors such as age, starting skin condition and lifestyle. Your practitioner can provide realistic before and after examples from their own work to help set appropriate expectations for your specific concerns and goals.