Yes, aftercare is absolutely essential for Dermamelan treatment and is one of the most critical factors determining your results. Unlike many other treatments where aftercare is helpful but optional, Dermamelan requires strict adherence to a comprehensive home care protocol for several months to achieve optimal results and prevent pigmentation from returning. The Dermamelan aftercare protocol includes Dermamelan Treatment Cream, a depigmenting cream applied daily at home for several months, which continues the pigment-inhibiting action started by the in-clinic treatment; Melan Recovery, a soothing balm used in the initial days to support healing; Melan Tran3x, a concentrated depigmenting gel for targeted application; and Mesoestetic Moisturiser and sunscreen as essential supporting products. The home care regimen typically involves applying the treatment cream twice daily initially, then once daily; strict sun protection with SPF 50+ reapplied throughout the day; avoiding sun exposure and heat as much as possible; and continuing the protocol for 6 to 12 months or longer. Why aftercare is so critical is because the in-clinic mask initiates the depigmentation process, but the home care maintains and builds upon these results; pigmentation can return quickly without consistent suppression of melanin production; the treatment addresses melanin at multiple levels, requiring sustained action; and sun exposure without protection can trigger immediate repigmentation. Failing to follow the aftercare protocol will likely result in disappointing results and potentially worsened pigmentation. The home care products are not optional add-ons but integral components of the treatment. When budgeting for Dermamelan, include the cost of several months of home care products, which can add significantly to the total investment. The commitment to aftercare is substantial but essential for achieving the significant pigmentation improvement Dermamelan can provide.

Prices for Dermamelan Peel vary between clinics depending on the severity of pigmentation and the personalised treatment plan. In the UK the price typically ranges from around £750 to £1950, though some clinics include follow-up care or prescription aftercare products in their fees. The cost is driven by factors such as the treatment area, number of sessions required, practitioner experience and any speciality aftercare. If you’re comparing options, search for how much Dermamelan Peel costs, the price of Dermamelan Peel and the cost of Dermamelan Peel overall to get a sense of value. You can find the exact, up-to-date price for this treatment in the catalogue

Dermamelan is a professional depigmentation treatment developed by Mesoestetic, designed to treat stubborn hyperpigmentation, melasma and dark spots. While often called a peel, Dermamelan is more accurately described as a depigmentation system that combines an intensive in-clinic mask treatment with an essential ongoing home care protocol. The treatment is considered one of the most effective non-prescription options for treating melasma and other forms of hyperpigmentation. The Dermamelan system consists of two main phases: the in-clinic treatment, where a professional mask containing multiple depigmenting agents is applied, left on for a specified time (typically 8 to 12 hours including time at home), then removed; and the home maintenance phase, where daily application of Dermamelan Treatment Cream and supporting products continues for several months to maintain and enhance results. Dermamelan works through multiple mechanisms including inhibiting tyrosinase, the enzyme responsible for melanin production; blocking melanin transfer to skin cells; accelerating cell turnover to shed pigmented cells; and regulating melanocyte activity long-term. The treatment can address melasma, including hormonal and UV-induced types; post-inflammatory hyperpigmentation from acne or injuries; sun damage and age spots; and general skin discolouration and uneven tone. Dermamelan is particularly valued for treating melasma, which is notoriously difficult to treat and often resistant to other interventions. The comprehensive approach addressing multiple steps in the pigmentation pathway makes it more effective than single-ingredient treatments. The treatment requires commitment to extensive aftercare and strict sun protection, but for appropriate candidates, it can provide significant, lasting improvement in stubborn pigmentation.

Dermamelan is not a traditional chemical peel but rather a professional depigmentation treatment that is sometimes categorised alongside peels due to its in-clinic application and skin renewal effects. Understanding what type of treatment Dermamelan actually is helps set appropriate expectations. Dermamelan differs from traditional peels in several ways. Traditional chemical peels use acids like glycolic, salicylic or TCA to exfoliate skin layers, cause controlled injury, and stimulate renewal. Dermamelan uses a combination of depigmenting agents that specifically target melanin production and transfer rather than primarily causing exfoliation. While some peeling may occur with Dermamelan, it is a secondary effect rather than the primary mechanism. The Dermamelan formulation contains multiple active ingredients targeting pigmentation including azelaic acid, kojic acid, phytic acid, retinol, vitamin C and other depigmenting agents. These work synergistically to inhibit melanin production at multiple points in the pigmentation pathway; reduce melanin transfer to skin cells; promote turnover of pigmented cells; and regulate melanocyte activity. If categorisation is needed, Dermamelan is best described as a depigmentation treatment or depigmentation peel; a melanogenesis-inhibiting treatment; a pigment-correcting system; or part of the category of cosmeceutical depigmentation treatments. The treatment is more comparable to other professional depigmentation systems like Cosmelan (also by Mesoestetic) rather than to traditional chemical peels like glycolic or TCA peels. The confusion arises because Dermamelan is applied like a mask or peel, can cause some visible peeling during healing, and is performed in clinical settings like other peels. However, its mechanism, ingredients and purpose are specifically designed for pigmentation correction rather than general resurfacing.

Dermamelan treatment is a comprehensive professional depigmentation system designed to treat stubborn hyperpigmentation, melasma and dark spots through a combination of in-clinic treatment and extended home care. Developed by Spanish cosmeceutical company Mesoestetic, it is considered one of the most effective treatments available for difficult pigmentation concerns. The treatment process involves several phases. During pre-treatment, skin is assessed and prepared, and you receive instructions for the treatment day. For the in-clinic application, the Dermamelan mask is applied by a trained practitioner and left on for a specified time, typically removed after 8 to 12 hours (you go home with the mask on and remove it yourself). During the immediate post-treatment period of days 1 to 7, the skin undergoes healing with redness, tightness, peeling and sensitivity. The home maintenance phase lasts months, involving daily application of Dermamelan Treatment Cream and supporting products. Active ingredients in Dermamelan work through multiple mechanisms: azelaic acid inhibits tyrosinase and has anti-inflammatory effects; kojic acid blocks melanin production; phytic acid provides antioxidant and brightening effects; retinol accelerates cell turnover; vitamin C provides antioxidant protection and brightening; and arbutin inhibits melanin synthesis. Dermamelan treatment can effectively address melasma including hormonal, pregnancy-related and sun-induced types; post-inflammatory hyperpigmentation; solar lentigines and age spots; and general hyperpigmentation and uneven skin tone. The treatment requires significant commitment including strict sun avoidance and protection; daily application of home care products for months; tolerance of a healing period with visible peeling and redness; and investment in ongoing maintenance products. For people with stubborn pigmentation that has not responded to other treatments, Dermamelan offers a powerful option with clinical evidence supporting significant improvement in pigmentation severity.

The standard Dermamelan formulation does not contain hydroquinone, which is one of its advantages for many patients and practitioners. Dermamelan uses alternative depigmenting agents to achieve its effects without relying on hydroquinone, making it suitable for longer-term use and for people who cannot or prefer not to use hydroquinone. Instead of hydroquinone, Dermamelan contains multiple alternative depigmenting ingredients including azelaic acid, which inhibits tyrosinase and has anti-inflammatory properties; kojic acid, a natural tyrosinase inhibitor derived from fungi; phytic acid, providing antioxidant and brightening effects; arbutin, a natural compound that inhibits melanin synthesis; retinol, accelerating cell turnover and improving penetration of other actives; vitamin C, offering antioxidant protection and brightening; and other proprietary ingredients targeting pigmentation. The absence of hydroquinone is significant because hydroquinone has restrictions in some countries due to safety concerns; it can cause ochronosis (paradoxical darkening) with prolonged use; some people experience irritation or sensitivity to hydroquinone; and it is typically recommended for limited duration use only. Dermamelan's hydroquinone-free formulation allows for extended treatment periods necessary for stubborn pigmentation; safer long-term maintenance protocols; use by people who cannot tolerate hydroquinone; and availability in regions where hydroquinone is restricted. The multiple depigmenting agents in Dermamelan work synergistically to provide comparable or superior results to hydroquinone-based treatments by targeting melanin production through several different mechanisms simultaneously. However, formulations can change over time, and regional variations may exist, so confirming the current ingredient list with your practitioner or checking the product packaging is advisable if hydroquinone avoidance is important to you for medical, regulatory or personal reasons.

Before Dermamelan treatment, people typically have stubborn hyperpigmentation that has not responded to other treatments; melasma presenting as brown or grey-brown patches, often on cheeks, forehead, nose or upper lip; post-inflammatory hyperpigmentation from acne, injuries or other skin trauma; sun damage with age spots and uneven pigmentation; significant impact on confidence and self-esteem due to visible pigmentation; and frustration after trying multiple other treatments with limited success. Melasma in particular is notoriously difficult to treat, often recurring despite various interventions, which is why many people turn to Dermamelan. After Dermamelan treatment, assessed 3 to 6 months after the initial treatment when full results have developed and the home care protocol has been followed, most appropriate candidates experience significant improvement. Common results include dramatic reduction in pigmentation intensity, often 50% to 80% improvement; more even, uniform skin tone; faded melasma patches becoming much less visible; reduced post-inflammatory marks; brighter, clearer overall complexion; and restored confidence about skin appearance. The degree of improvement depends on the type and depth of pigmentation, with some forms responding better than others; strict adherence to the home care protocol, which is essential; sun protection compliance, as any UV exposure can trigger repigmentation; individual response and skin characteristics; and whether pigmentation triggers like hormones or medications continue. During the treatment and recovery timeline, changes develop progressively: days 1 to 3 show redness, tightness and increasing sensitivity; days 3 to 10 involve significant peeling, flaking and shedding of pigmented skin; weeks 2 to 4 reveal skin settling with initial lightening visible; months 1 to 3 demonstrate progressive fading as home care continues; and months 3 to 6 show optimal results with continued maintenance. The peeling phase can be quite dramatic with significant visible shedding, requiring social downtime. Most people plan for 7 to 14 days of noticeable recovery. Before and after expectations should be realistic: Dermamelan provides significant improvement rather than complete elimination; melasma is a chronic condition that requires ongoing management; results require strict adherence to aftercare and sun protection; some pigmentation may return without continued maintenance; and deeper or hormonal pigmentation may be more resistant. Your practitioner should show realistic before and after photos demonstrating typical results for pigmentation similar to yours. Most satisfied Dermamelan patients are those who understand the commitment required for aftercare; follow the home care protocol diligently; maintain strict sun protection; and have realistic expectations about managing pigmentation long-term. For people with stubborn pigmentation who commit fully to the treatment protocol, Dermamelan can provide transformative results that significantly improve skin appearance and confidence, though ongoing maintenance and vigilance are required to sustain the improvement achieved.