HarmonyCA typically lasts 12 to 18 months or longer, with many people experiencing results lasting up to 2 years, making it one of the longer-lasting injectable treatments available. The extended duration comes from its unique hybrid formulation that combines immediate volumizing hyaluronic acid with calcium hydroxyapatite (CaHA) microspheres that stimulate long-term collagen production. The longevity has two phases: the hyaluronic acid component provides immediate volume and gradually breaks down over 6 to 12 months like traditional HA fillers; while the CaHA microspheres continue stimulating new collagen production for 12 to 18 months or longer, maintaining structural improvement even after the HA is absorbed. Several factors influence duration including the treatment area, with some areas potentially maintaining results longer than others; the amount injected, with appropriate volumes typically lasting longer; your individual metabolism and collagen production capacity; your age, with younger patients sometimes experiencing longer-lasting results; lifestyle factors including sun protection, skincare routine and healthy habits; and the injection technique and placement depth. The collagen stimulation effect means that even as the injected material gradually breaks down, your own newly produced collagen provides ongoing structural support, which is why results can persist longer than traditional HA fillers. Most practitioners recommend review appointments around 12 to 18 months after treatment to assess whether top-ups are needed. Some people find they need less frequent touch-ups compared to traditional fillers due to the collagen-building effect. The longevity makes HarmonyCA cost-effective for many people despite higher initial cost per syringe, as the extended duration means fewer treatment sessions over time.

Prices for HarmonyCA vary between clinics and depend on the personalised treatment plan. The price of HarmonyCA typically ranges from around £475 to £950, but final cost will reflect the specific product used, whether you need a single session or a course of treatments, the treatment area and your aesthetic goals. Practitioner experience and clinic reputation can also affect how much HarmonyCA costs, so ask about qualifications and what’s included in the fee. For a clear comparison of the price of HarmonyCA and the cost of HarmonyCA overall across providers, check our listings. You can find the exact, up-to-date price for this treatment in the catalogue

Whether HarmonyCA is worth it depends on your specific concerns, expectations, budget and treatment goals. For many people, HarmonyCA provides worthwhile benefits including longer-lasting results (12-24 months) compared to traditional HA fillers (6-12 months); dual action providing both immediate volume and progressive collagen stimulation; natural-looking results that develop and improve over time; versatility for various concerns including facial contouring, lifting and rejuvenation; and potential cost-effectiveness despite higher per-session cost due to extended duration. HarmonyCA is worth considering if you want both immediate improvement and long-term collagen building; prefer longer intervals between treatments; are suitable candidates for combination HA/CaHA products; want natural, progressive results rather than just immediate volume; and can afford the higher initial investment for longer-lasting benefits. However, it may not be worth it if you are unsure about committing to longer-lasting results, as HarmonyCA cannot be fully dissolved; prefer traditional fillers you are familiar with; have very limited budget making the higher cost prohibitive; want only immediate volumizing without collagen stimulation; or are not suitable candidates due to medical history or contraindications. Considerations include that HarmonyCA typically costs £400 to £700+ per syringe, more than traditional HA fillers; the CaHA component cannot be dissolved with hyaluronidase, so results are semi-permanent; treatment requires experienced injectors familiar with hybrid products; and results develop progressively, with final outcome visible months after treatment. For appropriate candidates seeking longer-lasting, natural results with collagen-building benefits, HarmonyCA often provides excellent value despite higher upfront cost. The extended duration means fewer appointments and less frequent treatments, which many people find worthwhile. However, the inability to fully reverse results means you should be very confident in your treatment goals and practitioner before proceeding.

HarmonyCA is a hybrid injectable product that combines two components in one formulation: hyaluronic acid (HA) gel for immediate volumizing and smoothing effects, and calcium hydroxyapatite (CaHA) microspheres for long-term collagen stimulation and bioremodelling. This unique combination provides both instant results and progressive, lasting improvement through natural collagen production. The treatment is designed for facial rejuvenation and contouring, addressing concerns including loss of volume and definition in cheeks, jawline and midface; wrinkles and folds requiring both filling and skin quality improvement; facial contouring and lifting without surgery; overall facial rejuvenation with natural-looking results; and skin quality improvement through collagen stimulation. HarmonyCA works through a dual mechanism: the HA component immediately adds volume, smooths lines and provides hydration; while the CaHA microspheres gradually stimulate fibroblasts to produce new collagen over several months, creating lasting structural improvement. The treatment is performed similarly to traditional dermal filler injections, using fine needles or cannulas to deliver the product to targeted areas. Results are visible immediately from the HA component, with progressive improvement developing over 3 to 6 months as collagen production increases. HarmonyCA is used by experienced injectors for comprehensive facial rejuvenation requiring both volume and collagen building; patients wanting longer-lasting results than traditional HA fillers; addressing mid-to-lower face concerns including cheeks, nasolabial folds, marionette lines and jawline; and creating natural-looking enhancement with progressive improvement. The product requires proper training and experience to use effectively, as it behaves differently from traditional single-component fillers and requires understanding of both immediate volumizing and long-term tissue remodelling effects.

HarmonyCA is classified as a dermal filler, but it is more accurately described as a hybrid biostimulator that combines characteristics of both traditional filler and collagen-stimulating treatments. Unlike pure hyaluronic acid fillers that only provide volumizing effects, or pure biostimulators like Sculptra that only stimulate collagen without immediate volume, HarmonyCA bridges both categories by providing immediate volumizing from its HA component and long-term collagen stimulation from its CaHA component. The distinction matters because traditional fillers simply add volume that gradually dissipates as the product breaks down; HarmonyCA provides initial volume that gradually transitions to naturally produced collagen, creating more natural, lasting improvement; pure biostimulators require multiple sessions and show no immediate results, while HarmonyCA offers instant gratification plus progressive enhancement; and the hybrid nature means it cannot be treated exactly like traditional HA fillers in terms of injection technique, expected results timeline or reversibility. HarmonyCA is used similarly to traditional fillers for volumizing and contouring, but requires understanding of both immediate filling effect and delayed collagen response, with results continuing to develop for months after injection. The product behaves like a filler immediately post-treatment, showing visible volume and contouring, but over time functions more like a biostimulator as your own collagen takes over from the injected material. This makes it suitable for people wanting both immediate results and long-term improvement, but means you must accept that results are largely non-reversible since the CaHA component and stimulated collagen cannot be dissolved. Most practitioners categorize HarmonyCA as an advanced or hybrid filler requiring specific training and experience beyond traditional HA filler injection. If you are considering HarmonyCA, understand that while it is technically a filler, it provides more comprehensive and longer-lasting effects than traditional fillers through its dual-action mechanism.

HarmonyCA cannot be fully dissolved, which is a critical consideration before treatment. The product contains two components: hyaluronic acid, which can be dissolved with hyaluronidase enzyme; and calcium hydroxyapatite (CaHA) microspheres, which cannot be dissolved and must be broken down naturally by the body over time. This means if you are unhappy with HarmonyCA results or experience complications, only the HA portion can be removed immediately, leaving the CaHA component and any collagen stimulation it has triggered in place. Important implications include that results are essentially semi-permanent, as the collagen-stimulating effect cannot be reversed; any volume or contour changes from the CaHA component will persist until naturally metabolized over 12-18+ months; complications or undesired results cannot be completely corrected immediately; and you must be very confident in your treatment goals and practitioner choice before proceeding. If problems occur with HarmonyCA, hyaluronidase can dissolve the HA component, reducing some immediate volume; but it cannot reverse the CaHA microspheres or stimulated collagen; you must wait for natural breakdown over many months; and in severe cases, surgical intervention might be needed to remove problematic CaHA, though this is rare. This lack of complete reversibility means HarmonyCA requires more careful consideration than traditional HA fillers, including being absolutely certain about your desired outcome; choosing a highly experienced injector familiar with hybrid products; starting conservatively, as you cannot easily correct overfilling; understanding and accepting the semi-permanent nature; and ensuring you are a suitable candidate with realistic expectations. The inability to fully dissolve HarmonyCA is not necessarily a disadvantage for appropriate candidates who want lasting results, but it does mean the commitment is greater than with traditional fillers. Many people view the longer-lasting results as an advantage, but you must accept that if you dislike the outcome, waiting for natural breakdown is your primary option. Always disclose if you have had HarmonyCA to any future practitioners, as they need to know about the presence of CaHA when planning additional treatments. If you are uncertain about committing to semi-permanent results or want the security of complete reversibility, traditional HA fillers might be more appropriate despite their shorter duration.

HarmonyCA filler typically lasts 12 to 24 months, with many people experiencing visible results for 18 months or longer, making it significantly longer-lasting than traditional hyaluronic acid fillers which typically last 6 to 12 months. The extended duration results from the unique dual-component formulation: the hyaluronic acid provides immediate volume and gradually breaks down over 6 to 12 months; while the calcium hydroxyapatite microspheres continue stimulating collagen production for 12 to 18 months or more, maintaining structural improvement even after the HA is absorbed. The longevity timeline typically follows this pattern: immediate results from HA volume are visible straight after treatment; weeks 1-3 see some settling as initial swelling resolves; months 1-6 show progressive improvement as collagen production increases; months 6-12 see the HA component gradually metabolizing while CaHA-stimulated collagen maintains results; and months 12-24+ show continued structural support from the newly produced collagen even as the injected material breaks down. Factors affecting duration include the treatment area, with some regions potentially maintaining results longer; the amount of product used, with appropriate volumes typically lasting longer; individual metabolism, with some people breaking down materials faster; age and natural collagen production capacity; lifestyle including sun protection, skincare and healthy habits; and injection technique, depth and placement. Some people find HarmonyCA lasts closer to 12 to 15 months, while others experience 18 to 24 months or occasionally longer of visible improvement. The progressive, natural-looking results mean that rather than suddenly disappearing, HarmonyCA gradually fades as your collagen production normalizes and the stimulated collagen slowly remodels. Most practitioners recommend review appointments around 12 to 18 months to assess whether top-up treatments are desired. The longer duration compared to traditional fillers makes HarmonyCA cost-effective despite higher per-syringe pricing, as you need fewer treatment sessions over time. This extended longevity is one of the primary advantages of choosing HarmonyCA over standard hyaluronic acid fillers, particularly for people seeking lasting results without frequent maintenance.

Before HarmonyCA treatment, people typically have concerns including volume loss in the midface, cheeks or other facial areas creating a hollow or aged appearance; loss of definition along the jawline or facial contours; wrinkles, folds or lines requiring both filling and improved skin quality; overall facial ageing with multiple concerns requiring comprehensive treatment; sagging or descent of facial tissues; or desire for facial enhancement and lifting without surgery. The face may appear deflated, aged or lacking the youthful contours and structure that have been lost over time. After HarmonyCA treatment, results develop in two phases providing both immediate and progressive improvement. Immediately after treatment (within days once swelling settles), people experience restored volume in treated areas from the HA component; improved facial contours and definition; smoothed wrinkles and folds; lifted appearance, particularly in the midface and jawline; and overall more youthful, refreshed facial appearance. Over the following 3 to 6 months, progressive enhancement develops as increased collagen production improves skin quality and structure; enhanced firmness and elasticity in treated areas; more natural-looking results as your own collagen takes over; improved skin texture and tone; and continued lifting and contouring effect. The degree of improvement varies considerably depending on starting facial structure and degree of volume loss, with moderate cases often showing dramatic improvement; the amount of HarmonyCA used and areas treated; individual collagen production response; realistic expectations about natural enhancement; and the skill and experience of the injector. When performed correctly by experienced practitioners, HarmonyCA provides natural-looking facial rejuvenation and contouring; improved volume and definition that looks like a refreshed version of yourself; progressive results that continue improving for months; and lasting enhancement maintaining results for 12-24 months. During the settling period, immediate swelling is common in the first few days; bruising may occur, particularly with needle technique; final aesthetic results are best assessed 2-4 weeks after treatment once swelling has completely resolved; and continued improvement develops over 3-6 months as collagen stimulation progresses. Because HarmonyCA combines immediate and progressive effects, before and after comparisons should be made at multiple timepoints: immediate post-treatment (after swelling settles), at 3 months (mid-collagen building phase), and at 6+ months (full collagen effect visible). The results should appear natural rather than overdone, with the face looking rejuvenated, lifted and more defined without appearing 'filled' or artificial. Your practitioner should provide realistic before and after photos from their own work showing results at various timepoints across different facial structures and treatment areas. Most appropriate candidates are very satisfied with HarmonyCA results, appreciating both the immediate improvement and the progressive, natural-looking enhancement that develops over time. The longer duration of results compared to traditional fillers is particularly valued, reducing the need for frequent maintenance treatments. However, it is crucial to have realistic expectations about natural enhancement rather than dramatic transformation, understand the progressive nature of results requiring patience, accept the semi-permanent nature since CaHA cannot be dissolved, and choose a highly experienced injector familiar with hybrid biostimulator products. For people seeking comprehensive facial rejuvenation with both immediate volume and long-term collagen building, HarmonyCA often provides excellent results that justify the higher cost and longer commitment compared to traditional fillers.